Jennings MB, Pollak R, Harkless LB, Kianifard F, Tavakkol A. Gupta AK, Scher RK, De Doncker P, Sauder DN, Shear NH. Oral treatments for toenail onychomycosis: a systematic review. An independent comparison of terbinafine and itraconazole in the treatment of toenail onychomycosis. A new classification system for grading the severity of onychomycosis: Onychomycosis Severity Index. Molecular detection of dermatophytes and nondermatophytes in onychomycosis by nested polymerase chain reaction based on 28S ribosomal RNA gene sequences. Long-term efficacy of antifungals in toenail onychomycosis: a critical review. Measuring health-related quality of life in onychomycosis. Fungal foot infection, cellulitis and diabetes: a review. The efficacy of fractional carbon dioxide (CO 2) laser combined with terbinafine hydrochloride 1% cream for the treatment of onychomycosis. Shi J, Li J, Huang H, Permatasari F, Liu J, Xu Y, et al. Laser treatment of onychomycosis due to Neoscytalidium dimidiatum: An open prospective study. Leverone AP, Guimarães DA, Bernardes-Engemann AR, Orofino-Costa R. The dermatopharmacologic profile of ciclopirox 8% nail lacquer. Trichophyton rubrum DNA strains are more stable in onychomycosis patients with persistent mixed infections involving a nondermatophyte mould. Risk-Based Estimate of Human Fungal Disease Burden, China. "If a nail looks different from normal that is usually due to physical damage (you stubbed your toe or dropped something on it) or a minor fungal infection that can be easily cleared up by a visit to the doctor" clarifies Jenkin.įor those worry-warts, he also adds not to send him any of your toenail clippings to analyze.Zhou LH, Jiang YK, Li RY, Huang LP, Yip CW, Denning DW, et al. In people with elevated amounts, it does not account for more that 0.003% of the toenail. Besides confirming their results, they must determine if arsenic concentrations in the toenail are modified with time.įor the time being, bad-looking toenails do not necessarily mean a person has been exposed to arsenic. The findings, part of PhD student Mark Button's project, have opened the way for a dozen new questions concerning arsenic exposure: How does it get to toenails? What may be a risk factor? Can the results be coupled to blood arsenic analysis? Gawan Jenkin from Leicester University is eager to find the answers, but first a larger study must be carried out. Hair samples can be used to measure exposure to high-levels, as those found in the bodies of King George III and Napoleon Bonaparte. Current methods of diagnosis include measuring its levels in urine or blood. In large doses, arsenic produces multi-system organ failure. The disruptions may then lead to defective, cancerous cells. When arsenic enters our body through food, water, dust, or soil, it disrupts metabolism. The method effectively detected high arsenic levels in all people in the study. It was then properly identified by inductively coupled plasma mass spectrometry, which detects metallic molecules accurately from small concentrations. Arsenic was isolated by acid digestion and microwave irradiation, which dissolves and precipitates metals. These were washed and freeze-dried to obtain a contamination-free toenail powder. The scientists first collected toe-nail clippings from people living near an abandoned arsenic mine. So how can our toe nails show how much of the infamous metallic element? The researchers from Nottingham Trent University, Leicester University, and the British Geological Survey published their findings on the Journal of Environmental Monitoring. Institution: London School of Hygiene and Tropical MedicineĪfter detecting high levels of arsenic in the earthworms living near a mine, British scientists came up with an unusual way to detect human exposure to the chemical - by testing toenail clippings.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |